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Effects of fundus laser on ocular surface parameters in diabetic retinopathy

Effect of panrentinal photocoagulation on ocular surface parameters in diabetic retinopathy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080192
Enrollment
Unknown
Registered
2024-01-23
Start date
2022-11-28
Completion date
Unknown
Last updated
2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetic retinopathy

Interventions

diabetic retinopathy patients who required PRP treatment (only 1 group):Pan-retinal laser photocoagulation (PRP)

Sponsors

The First Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1: Patients with proliferative or severe non-proliferative diabetic retinopathy requiring panrentinal photocoagulation 2: No communication barrier, can cooperate to complete all inspections 3: Willing to sign an informed consent form for the study

Exclusion criteria

Exclusion criteria: 1: Previous history of PRP treatment 2: Eyelid disease, nasolacrimal duct obstruction 3: Severe dry eye, concurrent use of contact lenses or topical ophthalmic drugs 4: Any corneal surgery (including laser refractive surgery and pterygium excision) 5: History of intraocular surgery 6: Cataract surgery within 3 months 7: lens opacity 8: Cannot cooperate with laser therapy or eye examination 9: Patients with tractor retinal detachment, massive vitreous hemorrhage, neovascular glaucoma and other conditions requiring surgery 10: Uncontrollable clinical problems during screening (such as serious mental, neurological, cardiovascular, respiratory, urinary and other systemic diseases)

Design outcomes

Primary

MeasureTime frame
Corneal staining score;

Secondary

MeasureTime frame
OSDI questionnaire score;Conjunctival tiger red staining score;Tear secretion;Number of goblet cell;Breakup time of tear film;

Countries

China

Contacts

Public ContactFenfen Yu

First Affiliated Hospital of Sun Yat-sen University

yufenfen3@mail.sysu.edu.cn+86 135 7049 4146

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026