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Study on the effect of injection modality on the efficacy of botulinum toxin in the treatment of androgenetic alopecia

Study on the effect of injection modality on the efficacy of botulinum toxin in the treatment of androgenetic alopecia

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080190
Enrollment
Unknown
Registered
2024-01-23
Start date
2023-08-31
Completion date
Unknown
Last updated
2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

androgenetic alopecia

Interventions

Bald area injection side:A total of 40-50u of botulinum toxin was injected intradermally at 20-25 injection sites in the balding area on the injected side of the baldness, and an equal amount of salin
Muscular area injection side:Lateral injections in the muscular area were given intramuscularly at 20-25 injection sites in the temporal and occipital muscular areas for a total of 40-50u of botulinum

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: ?Patients who are 18 years of age or older ? Patients diagnosed with androgenetic alopecia with manifestations of female pattern baldness, and with a BSAP classification greater than M3 ?Patients with no history of treatment with known interfering botulinum toxin medications within the past 6 months. ? Patients who are willing and able to complete re-injection at 3 months and 6 months after the first injection and follow-up at 9 months after the first injection. ? Patients with normal Chinese or English reading and comprehension skills. ? Patients who are not in pregnancy or breastfeeding.

Exclusion criteria

Exclusion criteria: ? Patients presenting with severe visceral, eye or skin diseases were excluded; ? Diseases of the neuromuscular system; ? Inflammation, infection or unhealed wounds of the skin around the head injection site; ? Systemic treatment with glucocorticoids or other immunosuppressive and immunomodulatory agents in the past 3 months.

Design outcomes

Primary

MeasureTime frame
Hair count;

Secondary

MeasureTime frame
Treatment Effectiveness Score;Patient satisfaction rating;

Countries

China

Contacts

Public ContactShu Zhang

Department of Dermatology, West China Hospital, Sichuan University.

shute33@163.com+86 185 8394 6832

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026