Nonarteritis anterior ischemic optic neuropathy
Conditions
Sponsors
Eye Hospital of China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age of onset: between 50-80 years, both sexes. 2. Duration of the disease: 1-5 months after the onset of the disease. 3. Clinical symptoms: onset of painless visual loss in one or both eyes; sudden onset of visual loss and/or visual field defects; optic disc edema with or without hard exudation from the hemorrhagic papillary bundles along the disc; changes in the optic disc corresponding to the visual field defects; and the exclusion of other ocular or systemic disorders that may contribute to the above clinical manifestations. 4. A crowded disc in the contralateral eye supports the diagnosis of NAION in the affected eye. 5. If the patient has a sequential onset in both eyes, and the onset of both eyes is within 1-5 months, the posterior eye will be included in the group. 6. systemic diseases such as blood sugar and blood pressure are well controlled.
Exclusion criteria
Exclusion criteria: 1. Ex-arterial inflammatory anterior ischemic optic neuropathy (no pain, no abnormalities in CRP or ESR). 2. Use of hormone therapy within one week before enrollment. 3. Other ocular diseases or refractive errors exceeding ±6.00 DS. 4. Patients with recurrent episodes of NAION in one eye. 5. Patients who refused to sign the informed consent form or withdrew their informed consent during follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Best corrected visual acuity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vision Field;Optical Coherence Tomography;Best corrected visual acuity;Patients with a worst visual acuity of less than 0.3 at onset improved the incidence of 3 rows or more; | — |
Countries
China
Contacts
Public ContactWang Ying
Eye Hospital,China Academy of Chinese Medical Sciences
Outcome results
None listed