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The effect of postoperative use of dexmedetomidine hydrochloride nasal spray on sleep in patients undergoing gynecological endoscopic surgery: randomized controlled clinical trial

The effect of postoperative use of dexmedetomidine hydrochloride nasal spray on sleep in patients undergoing gynecological endoscopic surgery: randomized controlled clinical trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080181
Enrollment
Unknown
Registered
2024-01-23
Start date
2024-01-31
Completion date
Unknown
Last updated
2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep disorders

Interventions

Control group:One night after surgery, give an equal dose of physiological saline nasal spray half an hour before going to bed
Experimental group:One night after surgery, 50 µ g of dexmedetomidine nasal spray was administered half an hour before going to bed

Sponsors

Guangzhou Women and Children's Medical Center
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Women aged 18-60 2. ASA level I-II 3. Accepting gynecological laparoscopic surgery 4. The surgery will end before 5 pm.

Exclusion criteria

Exclusion criteria: 1. Patients with preoperative sleep disorders (Pittsburgh Sleep Quality Index score = 7) 2. Patients with obstructive sleep apnea hypopnea syndrome 3. Those who take sedatives and antidepressants, have drug and alcohol dependence 4. Individuals with a history of mental illness, cardiovascular disease, nasopharyngeal carcinoma, nasal bleeding, and other nasal abnormalities.5. Having severe hearing or visual impairments, unable to communicate effectively, or refusing participants.6 Having a history of serious chronic diseases such as heart, brain, lungs, liver, and kidneys. 7. Individuals who are unable to understand the content of the scale and are allergic to experimental drugs 8. Anesthesia or surgical accidents occur during the operation.

Design outcomes

Primary

MeasureTime frame
Sleep Assessment Scale;Deep sleep duration;Sleep efficiency;Light sleep duration;

Secondary

MeasureTime frame
Hypotension;Bradycardia;Postoperative nausea and vomiting;

Countries

China

Contacts

Public ContactXi Chen

Guangzhou Women and Children's Medical Center

877579351@qq.com+86 186 2068 8567

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026