Cervical spondylosis
Conditions
Interventions
Uncovertebral fusion:Uncovertebral fusion
Traditional endplate fusion group:Using traditional zero profile fusion
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age range from 50 to 75 years old; (2) Single segment cervical spondylosis patients diagnosed based on clinical symptoms, signs, and imaging findings; (3) Those who have undergone standardized conservative treatment but are ineffective or have progressively worsened symptoms, affecting daily life and work, and require anterior decompression surgery; (4) The surgical segment is located between C3/4 and C6/7. (5) Be able to fully comply with this agreement psychologically and physiologically, and cooperate with the scheduled treatment plan, fill out forms, and follow up. (6) After the patient signs informed consent, it means that the patient is aware of and agrees to carry out the relevant aspects of this study. The above inclusion standards are internationally recognized standards to ensure rationality and feasibility.
Exclusion criteria
Exclusion criteria: (1) Previous history of cervical spine surgery and adjacent segmental bone fusion. (2) Ossification of the posterior longitudinal ligament or stenosis of the cervical spinal canal, spinal fractures, severe osteoporosis, or a history of bone metabolic diseases; (3) Local infection and ulceration of neck skin, systemic inflammatory disease, rheumatoid arthritis, uncontrolled diabetes, malignant tumor, active hepatitis, etc; (4) Individuals with mental illness or psychological disorders. (5) Poor overall condition, severe illness in important organs, and inability to tolerate surgery. (6) Known to suffer from infectious diseases such as AIDS, syphilis, etc. (7) I have received daily immunosuppressive therapy for more than one month in the past 12 months. (8) Allergy to implant materials (PPE or titanium alloy). (9) Severe obesity, history of drug abuse (10), pregnancy or pregnancy planning during the study period. (11) I am currently participating in other studies that may have an impact on the results of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fusion rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| JOA socer;NDI;VAS; | — |
Countries
China
Contacts
Public ContactLiu Hao
West China Hospital, Sichuan University
Outcome results
None listed