esophageal squamous cell carcinoma
Conditions
Interventions
18F-FDG-PET/MR group:None
Sponsors
The First Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Potential resectable esophageal squamous cell carcinoma patients (clinical TNM stage II-IIIexcluding adenosquamous carcinoma mixed type and other pathological types). 2. The score of ECOG or PS is 0 or 1. 3. Patients received neoadjuvant therapy of PD-1 inhibitor combined with chemotherapy. 4. The patients had whole body PET/CT and/or esophageal PET/MR examinations to determine the stage and exclude distant metastasis. 5. The patients have complete clinical and pathological data.
Exclusion criteria
Exclusion criteria: 1. Cervical esophageal cancer and gastroesophageal junction tumor confirmed by endoscopy. 2. Lack of PET CT and esophageal PRT/MR examination results before treatment and surgery. 3. Lack of biopsy pathology to confirm esophageal squamous cell carcinoma. 4. Have received other treatments except immunity and chemotherapy, such as radiotherapy, targeted therapy. 5. Patients with renal insufficiency, contraindication of magnetic resonance imaging, and severe allergic reaction to the Gadolinium contrast agent. 6. The following patients who are not suitable for magnetic resonance imaging (MRI), including cardiac pacemakers, metal artificial valves, intracranial and mediastinal vascular clips, cardiac defibrillators, nerve stimulators, implanted drug delivery systems, intraocular metal foreign bodies, cochlear implants, metal fragments of dangerous body parts within 8 weeks, Swan Ganz catheters and other metal implants: such as heart valves, stents, coils, filters and clips. 7. Patients with claustrophobia. 8. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area Under Curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| sensitivity;specificity;positive preditive value;negative preditive value;accuracy; | — |
Countries
China
Contacts
Public ContactChao Cheng
The First Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed