Perimenopausal Anxiety Disorder
Conditions
Interventions
the experimental group:Ningkun Jieyu Decoction
the control group:Femoston combined with Flupentixol and Melitracen Tablets
Sponsors
WANG JING HOSPITAL OF CACMS
Eligibility
Sex/Gender
Female
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Meeting the diagnostic criteria of western medicine for perimenopausal syndrome and anxiety disorder; classified as liver depression and heat syndrome by Chinese Medicine syndrome differentiation; women aged 40 to 60; Kupperman scale score > 6 points, 7 points = Hamilton anxiety score 10 U/L. 3.In accordance with Liver depression and heat syndrome. 4.Patients receiving anti-anxiety drugs and hormone therapy had not taken them before entering the trial or had stopped taking them several months earlier. 5.Patients who voluntarily agree to participate in this study, have good compliance, cooperate with treatment and sign informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients with bilateral ovariectomy, or ovarian tumors. 2.Patients with allergic constitution or allergy to traditional Chinese medicine. 3.Patients with severe primary diseases of cardiovascular, cerebrovascular, hepatic, renal and hematopoietic systems, as well as psychotic disorders such as severe depression and mania. 4.Patients with dementia, traumatic brain injury, intellectual disability, stroke, epilepsy and other neurological diseases. 5.Patients with dictation disorder who could not complete the scale assessment. 6.Patients who had participated or simultaneously participate in other clinical trial programs in the past 3 months. 7.Patients who had taken sex hormone drugs or drugs affecting sex hormone levels in the past month. 8.Patients who do not meet the inclusion criteria, or do not take the drug as prescribed, or withdraw voluntarily, or do not complete the indicators, or have serious adverse reactions during the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| E2;FSH;LH;5-HT;DA;Kupperman;Greene;MENQOL;Hamilton Anxiety Scale;TCM syndrome score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine ;Urine routine ;Liver and kidney function ;Electrocardiogram;Endometrial thickness;Vital signs; | — |
Countries
China
Contacts
Public ContactWang Hao
WANG JING HOSPITAL OF CACMS
Outcome results
None listed