Cognitive impairment after stroke
Conditions
Interventions
The Treatment Group:The intervention group underwent transcranial direct current stimulation (tDCS) stimulation, routine internal medical treatment, and conventional rehabilitation functional training
tDCS Sham Stimulation Group:The intervention group underwent transcranial direct current stimulation (tDCS) stimulation, routine internal medical treatment, and conventional rehabilitation functional
Sponsors
The Affiliated Rehabilitation Hospital, Fujian University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
35 Years to 80 Years
Inclusion criteria
Inclusion criteria: ? Age between 35 and 80 years old; ? First occurrence of cerebral stroke (hemorrhagic/ ischemic) with a duration of 2 weeks to 6 months; ? Diagnosis conforms to the diagnostic criteria of post-stroke cognitive impairment outlined in the "Expert Consensus on the Management of Post-Stroke Cognitive Impairment 2021"; ? MoCA (Montreal Cognitive Assessment) scores: =13 for illiterate individuals, =19 for 1-6 years of education, =24 for 7 years of education and above, with a total score of =8; ? No metallic implants or pacemakers in the body; ? Capable of understanding and cooperating with the rehabilitation assessment and treatment involved in this study; ? Right-handed; ? Informed consent form to be signed by the patient or their immediate family member.
Exclusion criteria
Exclusion criteria: ? Patients with cognitive impairment caused by other conditions such as brain tumors, senile dementia, hypothyroidism, or traumatic brain injury; ? Individuals with residual effects from lacunar infarctions in the past; ? Those with consciousness disorders, severe visual, auditory, or speech impairments; ? Patients with fever, electrolyte imbalances, or unstable vital signs; ? Individuals with severe dysfunction in vital organs such as heart, lungs, liver, or kidneys; ? Patients with contraindications to tDCS, such as local skin injuries or inflammation, skull defects, or those with tactile hypersensitivity in the stimulation area.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fuzhou version of MoCA scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| TMT-A;TMT-B;Rivermead Behavioral Memory Test-?;Rey-Osterrieth Complex Figure Test;Clock Drawing Test;Alpha power and frequency of resting EEG;The differences of local consistency and low frequency amplitude;The difference of FA value and ADC value in hippocampus, temporal lobe and parietal lobe;The latency and amplitude of event-related potential P300;Frequency domain and time domain parameters in heart rate variability (LF, HF, LF/HF and SDNN); | — |
Countries
China
Contacts
Public ContactXUPEITAO XUEXIEHUA(Graduate Supervisor)
The Affiliated Rehabilitation Hospital, Fujian University of Traditional Chinese Medicine
Outcome results
None listed