Chemotherapy-related cognitive impairment
Conditions
Interventions
acupucture group:acupuncture using reconciling qi and blood,tonifying heart and mind method
sham acupuncture group:the shallow acupuncture in non-acupoints and non-meridians
Sponsors
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University.
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients with histological, cytological, or radiographically confirmed triple-negative breast cancer.2.Age 18-65 years.3.Patients with cognitive impairment within 3 years after chemotherapy and have mild cognitive impairment.4.Syndrome differentiation of TCM belongs to QiXueShiTiao type.5.Expected survival of more than 1 year.6.Informed consent and voluntary signing of the Informed Consent Form.
Exclusion criteria
Exclusion criteria: 1.Suffering from mental disorders can interfere with cognitive function evaluation.2.Having alcohol dependence or abuse of other psychoactive substances; Taking medications that affect cognition in the last 3 months.3.Having severe visual acuity, hearing impairment, severe aphasia or dysgnosia.4.Having severe internal diseases or having central nervous system diseases,such as severe anemia, cacotrophy and so on.5.Those with brain metastases, encephalorrhagia,cerebral thrombosis,traumatic brain injury,or severe cardiovascular disease.6.Those who have received any cognitive rehabilitation within 3 months.7.Those who are unable to complete the relevant scale testing on their own for other causes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment, MOCA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mini-mental State Examination,MMSE;EORTC QLQ-C30;cytokine(TNF-a,IL-1ß,IL-2,IL-4,IL-5,IL-6,IL-8,IL-10,IL-12p70,IL-17,IFN-?,IFN-a); | — |
Countries
China
Contacts
Public ContactGao Chong
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University.
Outcome results
None listed