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Clinical Observation of Lidocaine Combined with Ciprofol for Induction and Maintenance of Total Intravenous Anesthesia in Laparoscopic Total Hysterectomy: A Prospective, Randomized, Controlled, Double-Blind Clinical Study

Clinical Observation of Lidocaine Combined with Ciprofol for Induction and Maintenance of Total Intravenous Anesthesia in Laparoscopic Total Hysterectomy: A Prospective, Randomized, Controlled, Double-Blind Clinical Study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080143
Enrollment
Unknown
Registered
2024-01-22
Start date
2023-04-01
Completion date
Unknown
Last updated
2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total intravenous anesthesia

Interventions

Group of LC:Ciprofol induction and maintenance
Lidocaine was continuously pumped intravenously
Group of C:Ciprofol induction and maintenance
Intravenous continuous pumping of equal amounts of normal saline

Sponsors

Nanfang Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1: Aged between 18 and 65 years 2: Patients undergoing elective laparoscopic total abdominal hysterectomy under gynecological general anesthesia 3: Anesthesiologists (ASA) physical status 1-II 4: Body Mass Index between 18 and 30 5: Written informed consent

Exclusion criteria

Exclusion criteria: 1: Significant liver and kidney diseases, psycho-nervous system diseases, heart failure, respiratory failure, etc 2: Severe arrhythmias: if there is a history of A-S syndrome, pre-excitation syndrome, or active dysrhythmia, concurrent treatment with Grade I antiarrhythmic drugs or amiodarone for less than 3 months 3: acute porphyria 4: Family history of malignant hyperthermia 5: Egg or soy allergy ; A history of allergy or hypersensitivity to the investigational drug that may be used in the study 6: Long-term use of sedatives or antidepressants 7: Inability to communicate or cooperate

Design outcomes

Primary

MeasureTime frame
The average dose of ciprofol;

Secondary

MeasureTime frame
Postoperative recovery quality;Safety and efficacy of intraoperative general anesthesia;

Countries

China

Contacts

Public ContactLin Chunshui

Nanfang Hospital of Southern Medical University

lcsnfyy@126.com+86 138 0278 4698

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026