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Study on the central regulatory mechanism of IC/BPS urination behavior based on brain functional magnetic resonance imaging

Study on the central regulatory mechanism of IC/BPS urination behavior based on brain functional magnetic resonance imaging

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400080138
Enrollment
Unknown
Registered
2024-01-22
Start date
2024-02-01
Completion date
Unknown
Last updated
2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Interstitial cystitis/painful bladder syndrome

Interventions

non-bladder disease group:None

Sponsors

Beijing Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) The main complaints were frequent urination, urgent urination, urination pain, suprapubic area and urethra pain when the bladder was full, relief after urination and other typical interstitial bladder inflammation; 2) Keep a 72-hour urination diary; 3) To improve the interstitial bladder inflammation Index scale (ICSI) and visual analogue Scale (VAS) to evaluate pain; 4) Meet the requirements of rs-fMRI examination; 5) Voluntarily participate in the research and sign the informed consent; 6) Able to communicate well with investigators and willing to comply with the requirements of the entire experiment.

Exclusion criteria

Exclusion criteria: 1) Pregnant, lactating and menstruating women; 2) Combined with uncontrolled urinary tract infection, urinary tract obstruction, urinary tract tumor; 3) Mental illness can not cooperate with the doctor; 4) The presence of non-urinary malignancies and other concomitant diseases that seriously affect health; 5) Clinically confirmed OAB and other diseases that induce bladder irritation symptoms; 6) Other circumstances in which the investigator considers it inappropriate to participate in the study; 7) Head movement exceeding 1.5mm or 1.5° during rs-fMRI; 8) People with contraindications in rs-fMRI

Design outcomes

Primary

MeasureTime frame
Functional brain areas;

Secondary

MeasureTime frame
ICPI score;ICSI score;OABSS score;IC-Qol score ;GRA score ;VAS score;Urination diary;

Countries

China

Contacts

Public ContactLingfeng Meng

Beijing Hospital

menglfdzs@163.com+86 185 1851 2987

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026