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Sevoflurane combined with different doses of intranasal dexmedetomidine in magnetic resonance sedation in children

Sevoflurane combined with different doses of intranasal dexmedetomidine in magnetic resonance sedation in children

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080133
Enrollment
Unknown
Registered
2024-01-22
Start date
2024-01-24
Completion date
Unknown
Last updated
2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The disease which need MRI test

Interventions

Sevoflurane group:Sevoflurane sedation
Intranasal dexmedetomidine 0.5 ug/kgplus sevoflurane group:Intranasal dexmedetomidine 0.5 ug/kg
Intranasal dexmedetomidine 1.0 ug/kg plus sevoflurane group:Intranasal dexmedetomidine 1.0 ug/kg
Intranasal dexmedetomidine 1.5 ug/kg plus sevoflurane group:Intranasal dexmedetomidine 1.5 ug/kg
Intranasal dexmedetomidine 2.0 ug/kg plus sevoflurane group:Intranasal dexmedetomidine 2.0 ug/kg
Intranasal dexmedetomidine 2.5 ug/kg plus sevoflurane group:Intranasal dexmedetomidine 2.5 ug/kg

Sponsors

Yuxi Children`s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 15 Years

Inclusion criteria

Inclusion criteria: Children with ASA physical status 1 to 3, aged 1 month ~15 years who scheduled for MRI test under sedation will be recruited

Exclusion criteria

Exclusion criteria: 1 Family members declined to participate in the study 2 Children with cyanotic congenital heart disease 3 Children with abnormal neurological or psychiatric development 4 weeks of gestation + preterm infants aged less than 42 weeks after birth 5 Children whose condition requires fasting 6 Children with known hepatic and renal impairment

Design outcomes

Primary

MeasureTime frame
duration of deep sedation;

Secondary

MeasureTime frame
satisfactory sedation rate;recovery time;onset time;side effects;

Countries

China

Contacts

Public ContactGuo Hongsong

Yuxi Children`s Hospital

309626473@qq.com+86 138 2601 2672

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026