Effect of doxofylline on recovery time of propofol: A prospective randomized controlled clinical trial

Strategies for rapid recovery and extubation after general anesthesia

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400080121

Enrollment

Unknown

Registered

2024-01-22

Start date

2024-01-25

Completion date

Unknown

Last updated

2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Experimental group:Doxofylline 2 mg/kg (15 ml) IV postoperatively

Control group:Saline 15ml IV postoperatively

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients undergoing hysteroscopic surgery under general anesthesia, aged 18 to 65 years, with American Society of Anesthesiologists (ASA) classification I to II. Propofol intravenous anesthesia is used. Anesthesia is administered with propofol intravenous anesthesia.

Exclusion criteria

Exclusion criteria: ? Patients with abnormal heart, brain, lung, liver and kidney function; ? BMI=28kg/m2.

Design outcomes

Secondary

Measure	Time frame
Stay length in PACU;Postoperative pain score;The incidence of delirium and emergence agitation;The incidence of hypertension and hypotension;The incidence of PACU hypoxian;Incidence of analgesic administration in the PACU;	—

Primary

Measure	Time frame
Anesthesia recovery time;	—

Countries

China

Contacts

Public ContactGuangqiu Zhu

Taizhou Hospital of Zhejiang Province

inchina888999@163.com+86 137 5760 9305

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026