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A study of the range of autoregulation of cerebral blood flow under one-lung ventilation and the factors influencing it

Study on the range of cerebral blood flow autoregulation and its influencing factors in intraoperative patients under NIRS monitoring

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400080120
Enrollment
Unknown
Registered
2024-01-22
Start date
2024-01-30
Completion date
Unknown
Last updated
2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative patients under NIRS monitoring in thoracic surgery

Interventions

Sponsors

Shanxi Baiqiu'en Hospital Shanxi Academy of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age 40-80 years old 2. ASA classification ? ~ ? 3. Patients undergoing elective thoracic surgery under general anesthesia with one-lung ventilation at our hospital 4. Participate in the study and sign the informed consent form

Exclusion criteria

Exclusion criteria: 1. patients who refused to participate in this experimental study 2. patients with intraoperative bleeding greater than 800 ml, with anesthesia or other food or drug allergies 3. Regular preoperative use of opioids or sedatives, antidepressants or anxiolytics 4. patients with cognitive dysfunction as assessed by the preoperative Mini-Mental Status Examination (MMSE) 5. patients with a history of previous brain injury central nervous system disease or neurosurgery 6. Those who are not suitable for clinical trials for other reasons in the opinion of the investigator and those who are participating in other clinical trial studies

Design outcomes

Primary

MeasureTime frame
regional cerebral oxygen saturation;mean arterial blood pressure;partial pressure of oxygen;partial pressure of carbon dioxide;hemoglobin concentration;lactic acid concentration;delirium;

Countries

China

Contacts

Public ContactPing Zhuang

Department of Anesthesiology, Shanxi Baiqiu'en Hospital

13700503507@163.com+86 137 0050 3507

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 8, 2026