stroke
Conditions
Interventions
experiment group:Brain-computer interface controlled robot training: including motor imagery of grasping different objects in daily life, including tennis balls, bowls, spoons, etc., involving task mo
control group:Robotic hand training (sham BCI condition) : The same hardware arrangement as in BCI training was used, including placing an EEG cap on the subject's head and fixing the hemiplegic hand
Sponsors
Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center)
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ? According to the diagnostic criteria of stroke in the 2015 Chinese Classification of Cerebrovascular Diseases ? Patients with the first stroke confirmed by head CT or MRI, 1 week to 3 months after stroke onset ? Male and female, aged from 18 to 80 years old ? The lesion was only in one hemisphere ? Severe unilateral upper limb motor dysfunction, FMA-UE score < 36 points ? Modified Ashworth scale =3, sitting balance =2 ? No severe cognitive and speech impairment, able to understand and complete therapist instructions (MMSE=21) ? No history of drug and alcohol dependence, severe liver and kidney function diseases, other diseases that may affect brain structure and function, and other mental disorders
Exclusion criteria
Exclusion criteria: ? History of two or more strokes ? The patients had limb dysfunction caused by other reasons before the onset of the disease or had recent upper limb fractures, severe arthritis, joint replacement surgery, and other factors affecting the upper limb function And ? Patients with other musculoskeletal and central nervous system disorders affecting functional recovery ? Patients with comprehension impairment, visual impairment, hearing impairment, complete aphasia, and severe cognitive impairment ? unstable condition or inability to actively cooperate with the training ? taking skeletal muscle relaxant drugs within 2 weeks or having a history of botulinum toxin injection in the past 6 months ? Metal implants in the body ? Other circumstances that the investigator deemed impossible to participate in a clinical trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer assessment-Upper Extremity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wolf Motor Function Test; Modified Barthel Index;resting motor threshold;motor evoked potential;central motor conduction time; | — |
Countries
China
Contacts
Public ContactJin Lingjing
Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center)
Outcome results
None listed