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RCT study on pregnancy outcomes of different timing of thawing and transfer in frozen-thawed single blastocyst transfer cycles

A comparative study of pregnancy outcomes in frozen-thawed transfer cycles with different timing of single blastocyst thawing transfer--a single-center, prospective, randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080114
Enrollment
Unknown
Registered
2024-01-21
Start date
2024-01-25
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

Control group :LH surge + 7 days thawing transplantation group
test group:Thawed transplantation 12 hours earlier.

Sponsors

the Second Affiliated Hospital of Air Force Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) Age < 40 years; (2) frozen-thawed embryo transfer cycles; (3) endometrial preparation protocol for natural cycles or microstimulation cycles; (4) D5/D6 high-quality single blastocyst transfer cycles without C.

Exclusion criteria

Exclusion criteria: (1) recurrent miscarriage (= 2 spontaneous abortions); (2) previous = 3 failed ET cycles (no implantation after transplantation); (3) combined uterine diseases (including uterine malformations, such as unicornuate uterus, bicornuate uterus, septate uterus and didelphys uterus, adenomyosis, uterine fibroids, endometrial polyps, intrauterine adhesions, etc.); (4) hydrosalpinx; (5) moderate to severe endometriosis (1996 American Society of Reproductive Medicine (ASRM) endometriosis criteria); (6) confirmed chromosomal abnormalities in both partners and/or the need for preimplantation genetic testing (PGT) operation; (7) participated in another clinical trial within the past 30 days; (8) suffering from other diseases that are contradictory to ART treatment or unable to tolerate pregnancy; (9) egg freezing cycle.

Design outcomes

Primary

MeasureTime frame
Blastocyst implantation rate per transfer cycle;

Secondary

MeasureTime frame
Ectopic pregnancy rate;HCG positive rate;Clinical pregnancy rate;

Countries

China

Contacts

Public ContactXiao He

the Second Affiliated Hospital of Air Force Military Medical University

HEXIAO8511@163.COM+86 136 6919 4397

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026