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Perioperative effects of transnasal nebulized fentanyl or sufentanil before general anesthesia

Perioperative effects of transnasal nebulized fentanyl or sufentanil before general anesthesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080110
Enrollment
Unknown
Registered
2024-01-20
Start date
2024-01-20
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip replacement surgery

Interventions

Fentanyl group:Transnasal nebulized fentanyl before general anesthesia
Sufentanil group:Transnasal nebulized sufentanil before general anesthesia
blank control group:None

Sponsors

The First Affiliated Hospital of Gannan Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) American Society of Anesthesiologist physical status Classification I-II (2) Age 18-65 years old (3) Proposed elective hip replacement surgery (4) Estimated duration of surgery 1-4h (5) The tracheal tube must be removed after the operation. (6) Voluntary informed consent

Exclusion criteria

Exclusion criteria: (1) a clear history of allergy to the drug under study (2) Alcohol or drug dependence (3) Opioid use within the past week (4) Presence of any intranasal pathology or congenital anomalies of the nose (5) Abnormal liver or kidney function (6) Severe dehydration and severe malnutrition (7) Mental abnormality or other reasons for not easy to cooperate (8) Peripheral neuropathy (9) Pregnant, lactating or planning to become pregnant in the near future (10) Inability to understand the content of the relevant scale or severe visual impairment.

Design outcomes

Primary

MeasureTime frame
VAS score for pain during arterial puncture;VAS score for pain during iliofascial nerve block;VAS score for pain during venipuncture;Injection Pain Verbal Rating Scale (VRS) score at induction of general anesthesia;—

Secondary

MeasureTime frame
Dosage of anesthetic drugs used;Dose of intraoperative interventional drugs used;Vital signs: MAP, HR, SpO2;Time between stopping the drug and removing the endotracheal tube;Recovery room awakening agitation score score and pain score;Surgery, anesthesia, recovery room time;Postoperative 24h pain score;Dosage of analgesic PCIA pump medication for 24h postoperative period;Postoperative sore throat condition;Patient satisfaction;Occurrence of adverse reactions;—

Countries

China

Contacts

Public ContactLi Chen

The First Affiliated Hospital of Gannan Medical University

2496700057@qq.com+86 157 2775 2168

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026