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The efficacy of different doses of intranasal dexmedetomidine on the prevention of emergence agitation in children undergoing tracheoscopy with sevoflurane anesthesia

Comparison of the efficacy of different doses of intranasal dexmedetomidine on emergence agitation prevention in children undergoing tracheoscopy with sevoflurane: A randomized controlled trial

Status
Unknown
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080091
Enrollment
Unknown
Registered
2024-01-19
Start date
2024-01-25
Completion date
Unknown
Last updated
2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tracheoscopy

Interventions

Sevoflurane group:Intranasal saline
Intranasal dexmedetomidine 0.5 ug/kg group:Intranasal dexmedetomidine 0.5 ug/kg
Intranasal dexmedetomidine 1.0 ug/kg group:Intranasal dexmedetomidine 1.0 ug/kg
Intranasal dexmedetomidine 1.5 ug/kg group:Intranasal dexmedetomidine 1.5 ug/kg
Intranasal dexmedetomidine 2.0 ug/kg group:Intranasal dexmedetomidine 2.0 ug/kg group

Sponsors

Yuxi Children`s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 15 Years

Inclusion criteria

Inclusion criteria: 1 ASA Level 1-3 2 Ages 1-15 3 Children undergoing tracheoscopy under sevolfurane

Exclusion criteria

Exclusion criteria: 1 Family members declined to participate in the study 2 Children with cyanotic congenital heart disease 3 Children with abnormal neurological or psychiatric development 4 weeks of gestation + preterm infants aged less than 42 weeks after birth 5 Children whose condition requires fasting 6 Children with known hepatic and renal impairment

Design outcomes

Primary

MeasureTime frame
Emergence agitation;

Secondary

MeasureTime frame
Intraoperative vital signs;Sedation scale;Side effects;

Countries

China

Contacts

Public ContactGuo Hongsong

Yuxi Children`s Hospital

309626473@qq.com+86 150 8770 8399

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 22, 2026