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Comparison of chloral hydrate and sevoflurane combined with intranasal dexmedetomidine for sedation in children with magnetic resonance imaging

Comparison of chloral hydrate combined with intranasal dexmedetomidine vs sevoflurane combined with intranasal dexmedetomidine for sedation in children with magnetic resonance imaging

Status
Unknown
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080088
Enrollment
Unknown
Registered
2024-01-19
Start date
2024-01-22
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Oral chloral hydrate plus dexmedetomidine group:2.0 ug/kg intranasal dexmedetomidine plus oral chloral hydrate 25mg/kg
Intranasal dexmedetomidine plus sevoflurane group:Intranasal dexmedetomidine 2.0 ug/kg plus sevoflurane

Sponsors

Yuxi Children`s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 10 Years

Inclusion criteria

Inclusion criteria: Children with ASA physical status 1 to 3, aged 0 ~10 years who scheduled for MRI test under sedation will be recruited

Exclusion criteria

Exclusion criteria: 1 Family members declined to participate in the study 2 Children with cyanotic congenital heart disease 3 Children with abnormal neurological or psychiatric development 4 weeks of gestation + preterm infants aged less than 42 weeks after birth 5 Children whose condition requires fasting 6 Children with known hepatic and renal impairment

Design outcomes

Primary

MeasureTime frame
Satisfactory sedation rate;

Secondary

MeasureTime frame
Duration of sedation;Recovery time;

Countries

China

Contacts

Public ContactGuo Hongsong

Yuxi Children`s Hospital

309626473@qq.com+86 150 8770 8399

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026