Children with airway foreign bodies, new organisms in the airway, airway stenosis, pneumonia, etc.
Conditions
Interventions
Group A:THRIVE+MJV ventilation management technology with a temperature of 37 degrees Celsius, oxygen flow rate of 0.2L/kg/min, and 100% oxygen concentration
Group B:THRIVE+MJV ventilation management technology with a temperature of 37 degrees Celsius, oxygen flow rate of 1L/kg/min, and 100% oxygen concentration
Group C:THRIVE+MJV ventilation management technology with a temperature of 37 degrees Celsius, oxygen flow rate of 2L/kg/min, and 100% oxygen concentration
Sponsors
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
2 Years to 8 Years
Inclusion criteria
Inclusion criteria: 1. Age range from 2 to 8 years old; 2. Revised pediatric ASA-PS scores ranging from I to III levels; 3. Proposed airway exploration surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Known or expected difficulty in intubation 2. Known or expected difficulty in mask ventilation 3. Oxygen dependence 4. Having congenital heart disease or respiratory developmental abnormalities 5. Contraindications to the use of neuromuscular blockade 6. Risk of reflux and aspiration 7. Individuals with a history of allergies to drugs used in anesthesia and surgery 8. Recent skull base/maxillofacial fractures 9. Patients with nasal congestion who cannot receive nasal ventilation (epistaxis/deviation of nasal septum, etc.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of SpO2 reduction to 95% after induction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Minimum intraoperative blood oxygen saturation value;The highest value of intraoperative percutaneous CO2;Mean blood oxygen saturation of children during surgery;Incidence of respiratory adverse events (RAEs) after airway establishment; | — |
Countries
China
Contacts
Public ContactHuiyan Hou
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed