advanced-age infertility
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Repeat ART treatment cycle, with no more than 2 previous IVF cycles and no blastocysts or frozen embryos; (2) Age = 35 years old, AMH = 1.2ng/ml, AFC = 5, 1-9 eggs obtained in the previous IVF; Or age<35 years old, AMH<1.2ng/ml (groups 2 and 3 that meet the Poseidon population classification criteria); (3) Having IVF indications, excluding contraindications, and using PPOS protocol to promote ovulation; (4) Those who meet the criteria for Western medicine diagnosis and traditional Chinese medicine syndrome differentiation; (5) Be aware of and voluntarily sign an informed consent form. Note: Only those who meet the above 5 criteria can be included.
Exclusion criteria
Exclusion criteria: (1) Those who still have remaining embryos in the previous IVF cycle; (2) Using non PPOS solutions to promote ovulation; (3) Individuals diagnosed with genital malformations or tumors through examination; Patients with severe primary diseases or mental illnesses; Patients with acute infectious diseases and organic diseases of the body; (4) Not cooperating with communicators; Note: Any one of the above four items is excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FTO;METTL3;YTHDC2; | — |
Secondary
| Measure | Time frame |
|---|---|
| Traditional Chinese Medicine Syndrome Points;Sex hormone levels; | — |
Countries
China
Contacts
Fujian Maternal and Child Health Hospital