Clinical study of liposomal bupivacaine for paravertebral nerve block analgesia after breast surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400080069

Enrollment

Unknown

Registered

2024-01-19

Start date

2024-01-30

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Analgesia after breast surgery

Interventions

Bupivacaine liposome group (LB group):Paravertebral nerve block:The patient was in a lateral position with the affected side of the body upward. A low frequency convex array probe was selected from th

Ropivacaine group (Group R):Paravertebral nerve block:The patient was in a lateral position with the affected side of the body upward. A low frequency convex array probe was selected from the sagittal

Eligibility

Sex/Gender

Female

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age 18-65 years old; ASA ? ~ ?; BMI < 30kg/m2

Exclusion criteria

Exclusion criteria: Long-term use of narcotic analgesics, hypnotics and known amides of local anesthetics allergic; Severe abnormal heart, lung, liver, kidney and coagulation function; Patients with mental system disease and puncture site infection

Design outcomes

Primary

Measure	Time frame
numerical rating scale;Ramsay calm score;Mean arterial pressure;Heart rate;Pulse oxygen saturation ;Total amount of esketamine used during the operation;Total amount of propofol used during the operation;Time to recover from anesthesia;The starting time of postoperative analgesic use and the cumulative dosage within 72 hours;	—

Countries

China

Contacts

Public ContactPengYue

The 8th Affiliated Hospital Sun Yat-sen University (Shenzhen Futian)

hg_84396959@sina.com+86 159 8668 6015

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026