Brain glioma
Conditions
Interventions
Case series:None
Sponsors
Sun Yat-sen University Cancer Center
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Patients with solitary supratentorial glioma diagnosed by imaging; 2) Craniotomy is recommended; 3) Aged between 18 and 75 years; 4) Gender is not limited; 5) Karnofsky score = 60; 6) Informed consent is obtained from the participant.
Exclusion criteria
Exclusion criteria: 1) Emergency surgery is needed; 2) MRI scan on the head cannot be completed; 3) multiple brain tumors; 4) screening MRI indicates non-tumoral cerebral hemorrhage; 5) screening MRI indicates acute or subacute cerebral infarction; 6) Pregnant or lactating women; 7) Pre-existing psychiatric diseases; 8) combine severe cardiovascular diseases or other critical diseases; 9) Previous history of intracranial hemorrhage; 10) Underwent severe trauma within three months, or unrecovered major surgery within four weeks prior to study enrollment 11) A history of drug and alcohol abuse in the past six months; 12) Participation in other clinical trials within 3 months prior to the study enrollment; 13) The investigators consider it inappropriate for participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change in mRS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| change in the volume of peritumoral edema ;Changes in the number and volume of infarct lesions adjacent to the surgical area;changes in the number of cerebral micro-infarct adjacent to the surgical area;Changes in the number and volume of hemorrhagical lesions adjacent to the surgical area;changes in the number of cerebral micro-bleed adjacent to the surgical area; | — |
Countries
China
Contacts
Public ContactZhongping Chen
Sun Yat-sen University Cancer Center
Outcome results
None listed