Adenoma of the colon
Conditions
Interventions
Experimental group:YiyiFuziBaijiang Powder
Placebo group:Placebo of YiyiFuziBaijiang Powder
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Pathologically definite diagnosis of progressive colorectal adenoma, defined as an adenoma with ?>25% villous structure ,? =10 mm in diameter or with high-grade intraepithelial neoplasia, meeting one of the above criteria; 2 Age 18-75 years; 3 Chinese medicine patients with spleen deficiency and dampness, stasis and heat obstruction, who are to be treated with traditional Chinese medicine; 4 Not taking antibiotics, aspirin, immunosuppressants, etc. within three months; 5 No serious cardiac, hepatic, renal or haematopoietic diseases and other factors affecting drug evaluation; 6 Those who have a relatively stable diet, can fill in the questionnaire completely and sign the informed consent voluntarily.
Exclusion criteria
Exclusion criteria: 1. Patients with gastrointestinal diseases, metabolic diseases, cardiovascular diseases, liver diseases, neurological diseases and autoimmune diseases with unstable conditions and unsatisfactory control effects; 2. Taking yoghurt or probiotics regularly for a long time (2-3 times/week for more than half a year); 3. Pregnant and lactating women; 4. Allergic to a certain drug in the prescription of Chinese medicine; 5. Participants in other clinical studies; 6. Those who are considered by the investigator to be unfit to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence; | — |
Secondary
| Measure | Time frame |
|---|---|
| Chinese Medicine Symptom Score;Gastrointestinal Symptom Score;immune function;microbial diversity;metabolomics; | — |
Countries
China
Contacts
Public ContactHua Sui
Shanghai General Hospital
Outcome results
None listed