head and neck squamous cell carcinoma
Conditions
Interventions
head and neck squamous cell carcinoma group:NA
Sponsors
Eye & ENT Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Able to understand and willing to sign a written informed consent document. 2. Pathologically diagnosed with squamous cell carcinoma of head and neck. 3. Age = 18 4. Male or female. 5. Hepatic function, renal function and normal blood test. Hepatic function: Alanine aminotransferase (ALT) = 2.5 upper limit of normal, Aspartate aminotransferase (AST) = 2.5 upper limit of normal. Serum total bilirubin = 1.5 upper limit of normal. Kidney function: Serum creatinine 60 ml/(min*1.73m2) (Cockcroft-Gault formula). Blood test: neutrophil (Neu) = 1.5×109/L, platelet (PLT) = 100×109/L, hemoglobin (HGB) = 90 g/L. 6. Good compliance.
Exclusion criteria
Exclusion criteria: 1. Patients who have participated in other clinical trials within 1 month before the test. 2. The investigator believes that it is inappropriate for individuals to participate in the trial: having, for example, severe acute or chronic medical conditions (including immune colitis, inflammatory bowel disease, non-infectious pneumonia, pulmonary fibrosis) or mental illness (including recent time [within the past year] or active suicidal ideation or behavior). 3. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Transcriptome characteristics;Metabolome characteristics;Genomic characteristics;Epigenetic characteristics; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proteome characteristics;Microbiome characteristics;Temporal and spatial transcriptome characteristics;Spatiotemporal metabolome characteristics;Characteristics of immune microenvironment; | — |
Countries
China
Contacts
Public ContactMing Zhang
Eye & ENT Hospital, Fudan University
Outcome results
None listed