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Effects of commercial fertilization medium on fertilization rate and embryo development in vitro

Effects of commercial fertilization medium on fertilization rate and embryo development in vitro

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400080019
Enrollment
Unknown
Registered
2024-01-18
Start date
2024-02-01
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

Study Group:Fertilization medium (Shenzhen Weituo Biotechnology Co. , Ltd.)
Control Group:GIVFTMPLUS((Vitrolife Sweden AB))

Sponsors

Hebei Maternity Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 38 Years

Inclusion criteria

Inclusion criteria: Stage one: 1. Female, age 20= age =38 years, number of oocytes obtained =5 oocytes, or female, age 20= age =38 years, self-paired study of =8 oocytes (sibling comparison, average oocyte allocation, use of different brands of fertilization medium) . 2. For in vitro fertilization-embryo transfer (IVF-ET) . 3. Both couples use germ cell for assisted reproduction. Stage two: 1. Female, age 20= age =38 years, self-paired study of =8 oocytes (sibling comparison, average oocyte allocation, use of different brands of fertilization medium) . 2. For in vitro fertilization-embryo transfer (IVF-ET) . 3. Both couples use germ cell for assisted reproduction.

Exclusion criteria

Exclusion criteria: 1. Husband with azoospermia or severe oligozoospermia requires Intracytoplasmic sperm injection (ICSI) . 2. The female subjects had systemic diseases, major endocrine or metabolic abnormalities that were not appropriate for the study. 3. History of ovarian, breast, uterus, pituitary or hypothalamus malignancy;. 4. A known history of chemotherapy or radiotherapy

Design outcomes

Primary

MeasureTime frame
Normal fertilization rate;

Secondary

MeasureTime frame
Cleavage rate;High quality embryo rate;Blastocyst formation rate;High quality blastocyst rate;Available blastocyst rate;

Countries

China

Contacts

Public ContactLiyi Cai

Reproductive Medical Center of Hebei Maternity Hospital

cai760829@163.com+86 159 6188 1808

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026