traumatic brain injury
Conditions
Interventions
Control group:None
Sponsors
Xuzhou Children's Hospital
Eligibility
Sex/Gender
All
Age
0.5 Years to 16 Years
Inclusion criteria
Inclusion criteria: 1. Have a clear history of traumatic brain injury, confirmed as TBI by head CT scan or magnetic resonance imaging (MRI) examination; 2. The time from injury to admission is less than 24 hours; 3. No previous neurological disease and brain trauma; 4. No other serious organic disease; 5. Informed consent of the children's parents.
Exclusion criteria
Exclusion criteria: Combined with central nervous system infection; surgical treatment in other hospitals before admittion; other prior systemic diseases including thyroid dysfunctions, malignancy, uremia, liver cirrhosis, and chronic heart or lung disease; refusal to participation or withdrew from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IL-1ß;GOS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| bcl-2 and adenovirus E1B19kDa-interacting protein 3;Beclin-1;GFAP;C3;S100A10;MMP-9;VEGF;IL-6; | — |
Countries
China
Contacts
Public ContactZhu Lei
Xuzhou Children's Hospital
Outcome results
None listed