The relationship between ventricular rate control level and cardiac remodeling in patients with early persistent atrial fibrillation: a prospective observational cohort study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2400079978

Enrollment

Unknown

Registered

2024-01-17

Start date

2019-03-10

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart failure and atrial fibrillation

Interventions

I group:Observation of left atrial diameter, left ventricular diameter, ejection fraction, and valve regurgitation data before and 1 year after enrollment in Group I

II group:Observation of left atrial diameter, left ventricular diameter, ejection fraction, and valve regurgitation data before and 1 year after enrollment in Group II

III group:Observation of left atrial diameter, left ventricular diameter, ejection fraction, and valve regurgitation data before and 1 year after enrollment in Group III

IVgroup:Observation of left atrial diameter, left ventricular diameter, ejection fraction, and valve regurgitation data before and 1 year after enrollment in Group IV

Eligibility

Sex/Gender

All

Age

50 Years to 75 Years

Inclusion criteria

Inclusion criteria: In terms of inclusion criteria, patients need to meet the following conditions: (1) aged between 50 and 75 years; (2) The initial diagnosis is persistent atrial fibrillation (atrial fibrillation lasting for more than 7 days but not more than 1 year); (3) Accompanied by rapid ventricular rate (ventricular rate = 100 beats/minute); (4) The size of the left atrium and left ventricle is within the range (left atrial diameter = 40mm, left ventricular end diastolic diameter = 50mm); (5) The range of ejection fraction is 50% -65%.

Exclusion criteria

Exclusion criteria: Exclusion criteria include: (1) various types of valvular heart disease; (2) Combined hyperthyroidism or confirmed hyperthyroid heart disease; (3) Slow fast syndrome; (4) Myocardial disease; (5) Planned restoration of sinus rhythm; (6) Change to sinus rhythm during follow-up period; (7) The 24-hour dynamic electrocardiogram indicates a long RR interval of>5 seconds. Each selected patient needs to sign the subject's informed consent form and be reviewed and approved by the ethics committee.

Design outcomes

Primary

Measure	Time frame
Left atrial diameter;Left ventricular diameter;Ejection fraction;Degree of valve regurgitation;	—

Countries

China

Contacts

Public ContactLiu Yongrong

People‘s hospital of chongqing hechuan

770586640@qq.com+86 151 2319 2344

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026