Diminished Ovarian Reserve
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meeting the diagnostic criteria for DOR; 2. meeting the diagnostic criteria of TCM kidney deficiency syndrome; 3. body mass index (BMI) is 18-25 kg/m2; 4.Women aged 20-40years ; 5. No use of hormone drugs for the first three months of treatment; 6. Willing to sign an informed consent form and voluntarily participate in the trial; 7. Approved by the Ethics Committee; 8. Comply with the Human Assisted Reproductive Technology Specification
Exclusion criteria
Exclusion criteria: 1. Those who do not follow the doctor's advice or are allergic to the ingredients of this Chinese medicine; 2. History of gynecological malignancy or radiotherapy/chemotherapy; 3. Infertility caused by genetic factors; 4. History of recurrent abortion; 5. The female reproductive tract has abnormal anatomical structure and does not have pregnancy function; 6. The woman is suffering from serious physical or mental illness and cannot bear pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of oocytes retrieved; | — |
Secondary
| Measure | Time frame |
|---|---|
| basal serum sex hormones;Rate of MII oocytes;Rate of 2 pronuclei (PN) fertilizations;Traditional Chinese Medicine syndrome score;Rate of High quality embryo ;Clinical pregnancy rate; | — |
Countries
China
Contacts
The Affiliated Hospital of Shandong University of Traditional Chinese Medicine