keloid
Conditions
Interventions
comparison group:non-intervention
test group:Sanjie Quban Formula:Take 1 sachet/dose (30 ml/sachet) of Dispersing Knot Dispelling Scarring Soup orally in the morning and evening for 1 month.
Sponsors
China-Japan Friendship Hospital
Eligibility
Sex/Gender
All
Age
1 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1: Keloid diagnostic criteria: cases were collected mainly from outpatients of the Department of Dermatology of China-Japan Friendship Hospital, and the included cases had to meet the clinical diagnostic criteria of keloid. Diagnostic criteria refer to the criteria proposed by Cai Jinglong et al: the mass is elevated on the skin surface, hard, smooth and shiny surface, irregular boundaries, no signs of regression within 1 year, the lesion exceeds the edge of the original injury, infiltrates into the surrounding normal tissues, and grows in the shape of a crab's foot with persistent growth, redness, pain and itching, and no tendency to self-healing, and it cannot subside by itself 2: Keloid Chinese medicine identification criteria: the combination of skin lesion identification and overall identification, scar color dark red, local tingling, refusing to press, pain is heavier than itching. Accompanied by forgetfulness, coercive pain, coercive distension, women may be accompanied by dysmenorrhea, the tongue has petechiae, ecchymosis, the pulse is thin and astringent, the evidence belongs to qi stagnation and blood stasis 3: The diagnostic criteria for keloids were met, and the skin lesions were identified as belonging to the Qi stagnation and blood stasis syndrome 4: One month after the scar is free of wounds or wounds are well healed and fully epithelialized 5: Subjects voluntarily enrolled in the study and signed an informed consent form
Exclusion criteria
Exclusion criteria: 1: Keloids that do not meet the diagnosis of Qi stagnation and blood stasis 2: Have other serious liver, kidney, heart and hematopoietic system diseases 3: Have significant psychiatric symptoms that prevent them from cooperating with the test 4: Pregnant women or other conditions deemed by the investigator to be unsuitable for participation in the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| efficient; | — |
Secondary
| Measure | Time frame |
|---|---|
| hypertrophic index, HI;Patient satisfaction ratings;Transcriptomics analysis results; | — |
Countries
CHina
Contacts
Public ContactLiu Qingwu
China-Japan Friendship Hospital
Outcome results
None listed