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Effects of different genders on the ED50 of anesthesia-induced remimazolam and differences in electroencephalographic characteristics in patients undergoing day surgery

Effects of different genders on the ED50 of anesthesia-induced remimazolam and differences in electroencephalographic characteristics in patients undergoing day surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079965
Enrollment
Unknown
Registered
2024-01-17
Start date
2024-01-18
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing day surgery

Interventions

Male group(M group):Male: Remimazolam 0.25 mg/kg
Female group(F group):Female: Remimazolam 0.25 mg/kg

Sponsors

The First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1) Patients undergoing elective day surgery, ASAI-III; 2) Age 18-65 years; 3) BMI 18.5-28 kg/m²; 4) No significant cardiopulmonary disease; 5) Normal communication; 6) Voluntary and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Severe respiratory and circulatory system diseases; 2. Neurological disorders; 3. Mental and psychological diseases; 4. Long-term drug abuse; 5. Complicated with obvious abnormal liver and kidney function; 6. Possible difficult airway; 7. People who are allergic to remimazolam and other narcotic drugs.

Design outcomes

Primary

MeasureTime frame
Median effective dose of remimazolam ;

Secondary

MeasureTime frame
Hemodynamic Indicators;time index;

Countries

China

Contacts

Public ContactTang Lili

The First Affiliated Hospital of Anhui Medical University

tanglilys@163.com+86 186 5411 0160

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026