Cough with pneumonia nodules
Conditions
Interventions
Experimental group:Take methyl sulfonate granules(8 weeks of treatment, 2 bags at a time, tid)
Sponsors
Hospital of Chengdu University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age = 18 years old and = 75 years old; 2. In line with the diagnostic criteria for cough and pulmonary inflammatory small nodules, CT scan or enhanced CT or PET-CT shows that both lungs have isolated solid nodules with a diameter of = 8mm; 3. Patients (including partners) have no infertility, sperm donation, egg donation plan and voluntary effective contraceptive measures from the signing of the informed consent to the end of the test; 4. After full informed consent, the patient voluntarily participates in the study and signs a written informed consent form, and agrees to comply with the procedures stipulated in the research plan;
Exclusion criteria
Exclusion criteria: 1. Those who are allergic to the experimental drugs in this study; 2. Patients with pulmonary nodules judged by researchers to require surgery or puncture biopsy; 3. Have malignant tumors (except for any type of in-situ cancer, basal cell and squamous cell skin cancer that has been completely removed or other tumors/cancers that have been radically treated and have no signs of disease for at least 3 years); 4. Alanine aminotransferase (ALT), almonine aminotransferase (AST) is greater than 3 × upper limit of normal value (ULN) 5. Pregnant and lactating women, or severe pulmonary and cardiac insufficiency, liver and kidney dysfunction, or other serious diseases that affect their survival, patients with severe trauma and major after surgery, mental patients; 6. Those who have participated in clinical trials of other drugs and devices within 3 months before selection (except those who have participated in other trials without drugs or intervention), or those who plan to participate in other clinical trials during the period of participation in this trial; 7. Other researchers believe that it is not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the score of the concise cough scale relative to the baseline on the 8th weekend after the first administration; | — |
Secondary
| Measure | Time frame |
|---|---|
| CT imaging shows the change of nodule diameter and baseline on the 8th weekend after the first administration; | — |
Countries
China
Contacts
Public ContactChen Chongli
Hospital of Chengdu University of Traditional Chinese Medicine
Outcome results
None listed