noncardiac surgery
Conditions
Interventions
OFA:Lidocaine 1.5mg/kg and ketamine 0.15mg/kg were administered intravenously, and maintained by pumping at 2mg/(kg · h) and 0.1mg/(kg · h), respectively.
OA:Administer sufentanil at 0.3ug/kg and pump remifentanil at 0.1ug/kg ·min for maintenance.
Sponsors
Yichang Central People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age: = 18 years old; 2. ASA level I to III; 3. Choose a scheduled non cardiac surgery; 4. The patient or their legal representative signs an informed consent form; 5. Planned to receive an arterial line during surgery; 6. Planned for elective non-cardiac non-day surgery with an expected duration of more than 2 hours.
Exclusion criteria
Exclusion criteria: Patients with heart failure, severe cardiac shunt, severe aortic stenosis, and severe arrhythmia were excluded. Patients with preoperative hypertension (MAP >100 mm Hg) or hypotension (MAP <65 mm Hg) and those requiring dialysis were also excluded. Patients scheduled for liver or vascular surgery were excluded due to the use of vascular clamping.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MAP during induction of anesthesia;HR during induction of anesthesia;Time weighted average of hypotension during induction of anesthesia;Time weighted average of hypertension during induction of anesthesia;The incidence of hypotension during induction of anesthesia;Incidence of hypertension during induction of anesthesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score;Nausea and vomiting;extubation time;Average dose of norepinephrine;Average dose of atropine;Time spent in hypotension;Time spent in hypertension;Percentage of time in hypertension;Percentage of time in hypotension; | — |
Countries
China
Contacts
Public ContactGong Yuan
Yichang Central People's Hospital
Outcome results
None listed