Esophageal variceal bleeding
Conditions
Interventions
Not grouped:Use an esophageal stent to stop bleeding
Sponsors
Eastern Theater General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) The subject voluntarily and signed the informed consent form of this trial; (2) Patients diagnosed with cirrhosis based on clinical manifestations, laboratory tests, imaging tests or liver biopsy; (3) Symptoms related to acute variceal upper gastrointestinal bleeding, such as hematemesis/melena/blood in the stool, before admission or during hospitalization (regardless of previous bleeding history); (4) Patients with endoscopic confirmation of esophageal variceal bleeding; (5) patients with hemodynamically stable before or after initial fluid resuscitation; (6) Age> 18 years old and < 75 years old.
Exclusion criteria
Exclusion criteria: (1) Endoscopic confirmation of non-simple esophageal variceal bleeding, such as gastric variceal bleeding or isolated gastric variceal bleeding; (2) tracheoesophageal fistula; (3) esophageal rupture; (4) Pharyngeal, larynx, esophagus, stomach or upper respiratory tract tumors; (5) esophageal stricture; (6) recent esophageal surgery; (7) pregnancy or breastfeeding; (8) Those who the investigator believes cannot be selected for any reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemostasis rate 5 days after treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Characteristics of the patient's population, such as type of cirrhosis, complications of cirrhosis, presence or absence of liver cancer;Surgical operation time and stent indwelling site;Whether there is blood transfusion and whether there is rescue treatment such as TIPS;Stent indwelling time;Hemostasis rate 6 weeks after treatment;Mortality at 5 days and 6 weeks after treatment;Child score and MELD score before and after stent treatment;Rate of stent-related adverse events such as stent displacement, dysphagia, aspiration pneumonia, mucosal ulcers, esophageal strictures, perforation, obstruction, infection, etc;Rate of rebleeding after removal of the stent after 5-7 days of treatment;Endoscopic appearance and rebleeding rate of varicose veins before and after secondary prevention;Cost effectiveness, such as length of hospital stay, hospital costs, total healthcare costs during follow-up; | — |
Countries
China
Contacts
Public ContactXuan Ji
Eastern Theater General Hospital
Outcome results
None listed