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Comparison of the effects of liposome bupivacaine and ropivacaine in thoracic paravertebral block on pain after thoracoscopic pulmonary wedgewise resection: a randomized controlled study

Comparison of the effects of liposome bupivacaine and ropivacaine in thoracic paravertebral block on pain after thoracoscopic pulmonary wedgewise resection: a randomized controlled study

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079880
Enrollment
Unknown
Registered
2024-01-15
Start date
2023-06-01
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary nodule

Interventions

Observation group:A mixture of liposome bupivacaine and bupivacaine hydrochloride for thoracic paravertebral nerve block
Control group:Ropivacaine hydrochloride for thoracic paravertebral nerve block

Sponsors

The First Affiliated Hospital of Xinxiang Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients between the ages of 18 and 80. Planned patients undergoing thoracoscopic lung wedge resection. Have appropriate cognitive and language skills to communicate effectively and understand pain assessment and post-operative follow-up procedures.

Exclusion criteria

Exclusion criteria: Pregnant or lactating women. Patients with severe cardiovascular disease, liver insufficiency, renal insufficiency, or other vital organ system diseases. Patients with a known allergy to local anesthetics or related drugs. Patients with known central nervous system disorders such as epilepsy or Parkinson's disease. Patients with bleeding predisposition or who are receiving anticoagulant therapy. Patients with mental illness, cognitive impairment, or other conditions that affect self-assessment of pain. Patients who have received interventional treatment related to pain perception (e.g. nerve block, physical therapy, etc.). Patients who have been treated with medications related to pain relief (such as analgesics, antidepressants, etc.). Patients unable to follow study protocols, including those unable to participate in follow-up.

Design outcomes

Primary

MeasureTime frame
Pain;Opioid use;

Secondary

MeasureTime frame
Postoperative complication;Time of first opiate use after surgery;

Countries

China

Contacts

Public ContactHongwei Zhang

The First Affiliated Hospital of Xinxiang Medical College

465791339@qq.com+86 185 3023 3961

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026