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Application of Targeted Liquid Therapy under Maintaining Systemic Vascular Resistance Index in Single Lung Ventilation Surgery

Application of Targeted Liquid Therapy under Maintaining Systemic Vascular Resistance Index in Single Lung Ventilation Surgery

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079872
Enrollment
Unknown
Registered
2024-01-15
Start date
2024-01-18
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Conventional liquid group (Group C):The total amount of fluid supplementation is preoperative fluid loss+physiological requirement+intraoperative fluid loss
Target oriented liquid therapy group (Group G) :Using TL-400 monitor to monitor hemodynamic parameters SVV and CI to guide fluid replacement

Sponsors

The First Affiliated Hospital of Gannan Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: ? Patients undergoing elective thoracoscopic pulmonary resection ? Age 18-75 years old ? ASA grade I-III ? BMI index 18.5-25.0kg · ? ? Cardiac function grades I-III

Exclusion criteria

Exclusion criteria: ? Arrhythmias ? Decompensated heart disease ? ASA Level IV ? Preoperative pulmonary dysfunction (FEV1<50% of predicted value) ? Preoperative hemoglobin<90g/L ? Preoperative renal dysfunction (creatinine above normal) ? Previous history of lung surgery ? Severe diseases of other organs combined.

Design outcomes

Primary

MeasureTime frame
The incidence of pulmonary complications; Record intraoperative inflow and outflow;

Secondary

MeasureTime frame
Record respiratory dynamics indicators before single lung ventilation (T0), 30 minutes of single lung ventilation (T1), 60 minutes of single lung ventilation (T2), 10 minutes of resumption of dual lung ventilation (T3), and at the end of surgery (T4);Record hemodynamic indicators before single lung ventilation (T0), 30 minutes of single lung ventilation (T1), 60 minutes of single lung ventilation (T2), 10 minutes of resumption of dual lung ventilation (T3), and at the end of surgery (T4);Dosage of vasoactive drugs used;The incidence of renal complications;Length of hospital stay;Gastrointestinal exhaust duration;

Countries

China

Contacts

Public ContactMaolin Zhong

The First Affiliated Hospital of Gannan Medical University

zml8802@163.com+86 136 0797 8802

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026