Anesthesia
Conditions
Interventions
esketamine 1 group:esketamine 0.05mg/kg/h
esketamine 2 group:esketamine 0.1mg/kg/h
esketamine 3 group:esketamine 0.15mg/kg/h
Sponsors
Huai’an First People’s Hospital of
Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients undergoing gastroenteroscopy. 2.American Society of Anesthesiologists (ASA) Class I - II patients. 3.Patients aged 20-65 years, BMI=30%.
Exclusion criteria
Exclusion criteria: 1.Patients with abnormal liver and kidney function tests or electrolyte disorders. 2.Patients received antidepressant, sedative and analgesic drugs within two weeks before surgery. 3.Patients with contraindications to use related drugs. 4.Patients with myocardial infarction, poorly controlled hypertension (systolic blood pressure > 180mmHg), cerebrovascular disease. 5.Language or body dysfunctions who could not cooperate to complete the scales. 6.Patients with sleep apnea syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| somatic responses;blood pressure;Pulse oxygen;heart rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mini-mental State Examination;Montreal Cognitive Assessment ;recovery time;Time to leave the recovery room; | — |
Countries
China
Contacts
Public ContactLijun An
Huai’an First People’s Hospital of Nanjing Medical University
Outcome results
None listed