diabetic kidney disease
Conditions
Interventions
intervention group:Fenalidone
control group:no(treatment guidelines)
Sponsors
Hebei Yiling Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) Type 2 diabetes patients; 2) Age range from 40 to 85 years old, regardless of gender; 3) Estimated glomerular filtration rate (eGFR)>15 ml/min/1.73 m2 (CKD-EPI formula); And or 24 hour urine protein quantity>0.5g or kidney disease symptoms in patients with diabetes and kidney disease. 4) Glycated hemoglobin (HbA1c) = 6.5%, = 12.0%; 5) Be able to understand the procedures and methods of this clinical study, correctly express willingness, voluntarily participate and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Non T2DM patients; 2) T2DM patients with known malignant tumors, or lactic acidosis, or ketoacidosis, or severe infections, or critically ill patients (such as organ failure, heart failure, myocardial infarction, cerebral infarction, etc.); 3) Have a history of primary thyroid disease and a history of thyroid autoimmune disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal flora;Systemic immune inflammation index;Urinary protein creatinine ratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine;renal function,Blood cholesterol and triglycerides;Coagulation indicators, immunoglobulins, C-reactive protein, fasting blood glucose; | — |
Countries
China
Contacts
Public ContactLiHuiFang
Nephrology Department of Yiling Hospital Hebei
Outcome results
None listed