Neonatal ischemic hypoxic encephalopathy
Conditions
Interventions
Gold Standard:Gold standard: combined with the results of cranial magnetic resonance imaging and two senior pediatric radiologists (experience > 10 years), the brain ultrasound images and relevant cli
Index test:1. The gestational age (weeks), birth age (days), sex, weight (g), heart rate, respiratory rate, oxygen saturation, history of ischemia and hypoxia, Apgar score of 1, 5 and 10 minutes, musc
Each image consists of 6 static images +2 dynamic videos
Sagittal planes: 1) acquire and save images in the median sagittal plane (1 image), left parasittal plane (1 image), and right parasittal plan
2) acquire and save video by slow and steady scanning from the left insular plane to the right insular plane for a duration of 6-10s.
Coronal plane: 1) Acquire and save still images of the anterior a
2) Acquire and save video by slow and steady scan from frontal plane to occipital plane for 6-10s. Acquire and save these images and videos separately using linear array probes (trapezoidal imaging) a
Sponsors
Shenzhen Children's Hospital
Eligibility
Sex/Gender
All
Age
0 Years to 0.5 Years
Inclusion criteria
Inclusion criteria: 1) Healthy newborns with no known diseases; 2) Newborns or infants with suspected HIE or intracranial hemorrhage; 3) Newborns or infants suspected of having other brain abnormalities.
Exclusion criteria
Exclusion criteria: 1) Newborns or infants who are unable to complete a brain ultrasound scan due to any circumstances; 2) Newborns or infants whose final diagnosis is unclear.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 2D ultrasound image; | — |
Secondary
| Measure | Time frame |
|---|---|
| Brain MRI results;EEG findings;Liver function test results;Renal function (creatinine);Myocardial injury marker (creatine kinase) levels; | — |
Countries
China
Contacts
Public ContactLuyao Zhou
Shenzhen Children's Hospital
Outcome results
None listed