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Application of dexmedetomidine nasal drops in preventing and treating shivering reactions in patients undergoing cesarean section under epidural anesthesia

Application of dexmedetomidine nasal drops in preventing and treating shivering reactions in patients undergoing cesarean section under epidural anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079811
Enrollment
Unknown
Registered
2024-01-12
Start date
2024-01-15
Completion date
Unknown
Last updated
2024-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shivering

Interventions

control group:Use 1ml of physiological saline nasal drops before epidural anesthesia
Experimental group:Use dexmedetomidine 1ug/kg nasal drops before epidural anesthesia

Sponsors

The Second Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age > 18 years old; ASA grading I to II; Patients planning to undergo cesarean section surgery

Exclusion criteria

Exclusion criteria: Emergency cesarean section; General anesthesia surgery; Weight less than 60kg or greater than 120kg; Patients who are allergic to dexmedetomidine; Patients with severe systemic diseases of the heart, kidneys, and liver; Patients with preeclampsia or eclampsia; Combined spinal epidural anesthesia; Intraoperative blood transfusion or serious complications may occur.

Design outcomes

Primary

MeasureTime frame
Frequency of shivering reactions;Duration of shivering response;Classification of shivering response;Neonatal birth score;

Secondary

MeasureTime frame
Sedation level grading;Nausea and vomiting frequency;Surgical time;Oropharyngeal temperature;Supplemental dosage of analgesics;Total usage of ropivacaine;

Countries

China

Contacts

Public ContactLi Rui

Department of Anesthesiology and Perioperative Medicine, the Second Affiliated

lrayd@sina.com+86 138 5511 4159

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026