Ovarian cancer
Conditions
Interventions
Experimental group (Neoadjuvant chemotherapy regimen containing doxorubicin):None
Control group (No doxorubicin neoadjuvant chemotherapy regimen):None
Sponsors
Zhejiang Cancer Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Age =18 years, =80 years, gender female; 2) Ovarian cancer patients receiving neoadjuvant chemotherapy with or without doxorubicin liposomes; 3) ASA grade I or II; 4) Clearly understand and voluntarily participate in the study, and have their own or their family members sign informed consent.
Exclusion criteria
Exclusion criteria: 1) The patient had non-chemotherapy-related myocardial ischemia, arrhythmia, or myocardial injury before chemotherapy; 2) ASA grade =?; 3) Hb 2 units of alcohol (1 unit =360mL beer or 45mL liquor with 40% alcohol or 150mL wine); 10) Patients with craniocerebral injury, possible history of convulsion, myoclonus, intracranial hypertension, brain aneurysm, cerebrovascular accident; Patients with schizophrenia, intellectual disability, mania, insanity, long-term use of psychotropic drugs, drug addiction, cognitive dysfunction, etc.; 11) Patients considered by the investigator to be unfit to participate in this study. 12) Patients with a history of chemotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Iron death test index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Myocardial zymogram;electrocardiogram; | — |
Countries
China
Contacts
Public ContactXu Pingbo
Zhejiang Cancer Hospital
Outcome results
None listed