None
Conditions
Interventions
High-dose sufentanil group:Sufentanil 0.35ug/kg
Low dose sufentanil group:Sufentanil 0.25ug/kg
Sponsors
Nanchong Central Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients who underwent daytime hysteroscopic resection were aged between 18 and 65 years. 2. Body mass index 18-28kg/m^2; 3. ASAI - Class II; 4. Patients who agree to sign informed consent.
Exclusion criteria
Exclusion criteria: 1. A history of diseases of the nervous, muscular and endocrine systems; Serious organic diseases, such as serious heart, lung, liver, kidney, brain and other disorders; 2. Poorly controlled hypertension such as systolic blood pressure =180mmHg or diastolic blood pressure =110mmHg; 3. Acute respiratory infections, COPD, and poorly controlled asthma 4. A history of long-term use of neuropsychiatric drugs such as antidepressants and anti-anxiety drugs or a history of benzodiazepines in the past three months; Cardiac hand Surgical history, cerebrovascular accident history, alcoholism history; 5. People who are allergic to the study drug; 6. Patients with expected difficult airway; 7. Pregnant and lactating women; 8. There are social psychological problems and other reasons can not cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Median effective dose of Remimazolam; | — |
Secondary
| Measure | Time frame |
|---|---|
| Remazolam 95% effective dose;Patients' vital signs (SBP,DBP,MAP, HR, SPO2) at various time points during anesthesia induction;Number of adverse reactions during induction and within 5 minutes after laryngeal mask placement (hypotension, bradycardia, hypoxemia, injection pain, etc.);Number of postoperative adverse reactions (intraoperative awareness, postoperative nausea and vomiting, etc.);Demographic indicators (such as age, weight, height, etc.); | — |
Countries
China
Contacts
Public ContactXie Ying
Nanchong Central Hospital
Outcome results
None listed