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18F-FAZA PET hypoxic imaging of malignant tumors

18F-FAZA PET hypoxic imaging of malignant tumors

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079784
Enrollment
Unknown
Registered
2024-01-11
Start date
2024-01-04
Completion date
Unknown
Last updated
2024-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-small cell lung cancer

Interventions

One:The dose of radiotherapy was adjusted according to the hypoxic region after 18F-FDG and 18F-FAZA image registration
Two:Treated with standard radiotherapy

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Patients with pathologically confirmed malignant solid tumors. (2) Age= 18 years old. (3) Sign the informed consent form. (4) Standard method imaging is not more than 8 weeks. (5) The patient has sufficient understanding and behavioral capacity to understand and comply with the terms of the informed consent form approved by the ethics committee.

Exclusion criteria

Exclusion criteria: (1) During lactation. (2) Pregnant or already pregnant within 6 months of planning. (3) Impaired renal function, creatinine clearance less than 40ml/min. (4) Age< 18 years old. (5) Patients who have not signed the informed consent form or are unable to cooperate.

Design outcomes

Primary

MeasureTime frame
SUVmax;SUVmean;TBR;fractional hypoxic volume;Sensitivity;Specificity;Overall survival, OS;Progression-free survival, PFS;

Secondary

MeasureTime frame
GTV;MTV;

Countries

China

Contacts

Public ContactRong Tian

West China Hospital of Sichuan University

rongtiannuclear@126.com+86 189 8060 1586

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026