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Biomechanical and biological Characteristics of Macula during Accommodation in High Myopia with Different Posterior Scleral Shapes

Biomechanical and biological Characteristics of Macula during Accommodation in High Myopia with Different Posterior Scleral Shapes

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400079777
Enrollment
Unknown
Registered
2024-01-11
Start date
2024-01-11
Completion date
Unknown
Last updated
2024-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myopia

Interventions

Observation group:None

Sponsors

Beijing Tongren Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1: aged 18 to 40 years 2: Volunteer to join the study

Exclusion criteria

Exclusion criteria: 1: best corrected visual acuity<20/400 2: Uveitis, glaucoma, age-related macular degeneration, retinal vascular occlusion, choroidal neovascularization, retinoschisis, epiretinal membrane, Vitreous macular traction, Patchy chorioretinal atrophy, lacquer cracks, Fuch‘s spot, macular atrophy, and other fundus lesions 3: a history of ocular trauma that affected visual function 4: High myopia secondary to other ocular diseases, such as congenital cataract, FEVR, Stickler syndrome, etc 5: High myopia secondary to ocular structural abnormalities, , such as spherical crystals and keratoconus 6: Any condition that may affect the results of the clinical trial in the opinion of the study physician(subjects are prone to nervousness, uncontrollable emotions, depression, poor compliance, mental and physical conditions unable to cooperate with the corresponding ophthalmic examination, etc)

Design outcomes

Primary

MeasureTime frame
Retinal strain value in the macular region;axial length;Posterior staphyloma height;

Secondary

MeasureTime frame
Retinal strain value around the optic disc;Anterior segment parameters (anterior chamber depth, pupil diameter, lens position, lens thickness);color fundus images;Peripheral ocular parameters (ciliary body morphology, peripheral choroidal thickness);best corrected visual acuity;intraocular pressure;3D-ocular shape;Changes in choroidal blood flow index;

Countries

China

Contacts

Public ContactTian Jiaxin

Beijing Tongren Hospital, Capital Medical University

jiaxin961@qq.com+86 188 1086 2895

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026