Multimodal MRI study on the regulatory mechanism of ApoE gene polymorphism on neural circuits in preclinical Alzheimer's disease patients

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2400079773

Enrollment

Unknown

Registered

2024-01-11

Start date

2024-01-15

Completion date

Unknown

Last updated

2024-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preclinical Alzheimer's disease patients

Interventions

Observation group:None

Eligibility

Sex/Gender

All

Age

55 Years to 100 Years

Inclusion criteria

Inclusion criteria: ? Age = 55 years old; ? Able to communicate normally in Mandarin; ? Has a certain level of understanding and judgment ability, is aware of the investigation purpose, and agrees to participate.

Exclusion criteria

Exclusion criteria: ? AD patients with mental and behavioral abnormalities; ? Severe hearing or language impairment; ? Individuals with severe physical illness who are unable to cooperate in completing the investigation; ? Participants in MRI examinations are excluded from those with metal implants such as pacemakers, nerve stimulators, arterial stents, artificial metal heart valves, aneurysm clips (excluding non paramagnetic titanium alloys), metal foreign body residues near important organs, and those with claustrophobia.

Design outcomes

Primary

Measure	Time frame
General Data Sheet;MRI scan;	—

Countries

China

Contacts

Public ContactYan yuanjiao

Fujian provincial hospital

yuanjiao1994@126.com+86 181 2082 6271

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026