tourniquet pain
Conditions
Interventions
Ropivacaine group:The epidural cavity was given 2% lidocaine 3ml and 0.5% ropivacaine 14ml
Dexmedetomidine combined with ropivacaine group:3ml 2% lidocaine +0.5% ropivacaine + dexmedetomidine solution (1µg/kg) 14ml was given in the epidural space
Sponsors
Shaoxing People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing lower extremity surgery with epidural anesthesia and tourniquet. 2, Age: 18 to 65 years old, BMI: 18.5-25. 3. Have certain communication skills and learn to use VAS score. 4. Volunteer to participate in this experiment.
Exclusion criteria
Exclusion criteria: 1. History of hypertension. 2, diabetes, nervous system damage and other sensory disorders. 3. Contraindications of epidural anesthesia such as infection of puncture point and coagulation dysfunction. 4. Known allergic history of local anesthesia drugs and auxiliary drugs used. 5. Severe cardiopulmonary function, including NYHA grade ?-IV, acute pneumonia or asthma. 6, liver and kidney dysfunction, including alanine aminotransferase (ALT) or aspartate aminotransferase (AST) = 2 times the upper limit of normal and blood creatinine (Cr) = 1.5 times the upper limit of normal. 7. A history of dependence on alcohol, opioids, and other analgesic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of tourniquet pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of occurrence of tourniquet pain;Fentanyl usage;The incidence of change general anesthesia;Time of tourniquet pain;Fentanyl use;Change the incidence of general anesthesia; | — |
Countries
China
Contacts
Public ContactMochi Guo
Shaoxing People's Hospital
Outcome results
None listed