Aggressive fibromatosis, low-grade liposarcoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? pathologically diagnosed aggressive fibromatosis and low-grade liposarcoma; ? aged 6-70 years; ? tumor located at extremities and involving adjacent major vessels and/or nerves, and R0 resection margin cannot be achieved while preserving involved vessels and/or nerves; ? progressive aggressive fibromatosis during active surveillance or adjuvant therapy. ? Consideration of medical history, clinical, laboratory and imaging examinations, scores, etc., to determine whether surgical treatment can be tolerated; ? Agree to join this study and sign the consent form. The compliance is good and consistent.
Exclusion criteria
Exclusion criteria: ? Patients with serious heart, liver and kidney diseases, pregnant or lactating patients; ? Uncorrectable bleeding tendency or coagulation dysfunction; ? Presence of systemic infection or puncture site infection; ? According to the judgment of the researcher, the patient may have other factors that may lead to the forced midway termination of this study, such as other serious diseases or serious laboratory abnormalities, or other factors that will affect the safety of the subject, unable to tolerate surgical treatment, or the family or society of the test data and sample collection;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3-year event-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effect occurrence rate ; | — |
Countries
China
Contacts
The First Affiliated Hospital of Sun Yat-Sen University