Burns
Conditions
Interventions
Active cell membrane group:Covering a membrane infiltrated with active allogeneic cells
Freeze-dried cell membrane group:Covering a membrane infiltrated with freeze-dried allogeneic cells
Sponsors
Department of Burns and Plastic Surgery, The Fourth Medical Center of Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ? The burn area is within the range of 1%-30%TBSA, and the single observable wound surface is not less than 8×8 cm2.? Selected patients should be voluntary, fully understand and voluntarily sign informed consent.?Age 18-60 years old, gender is not limited.? Outpatient or inpatient, within 5 days after injury.? Female patients of childbearing age should have effective contraceptive methods during the trial.
Exclusion criteria
Exclusion criteria: ? Patients with a clear history of malignant tumors, AIDS, autoimmune diseases, and organ transplantation.? Pregnant or lactating patients.? Patients with myocardial infarction and cerebrovascular accident within 6 months.?According to the comprehensive evaluation of the researchers, the poor willingness of patients and their families to treat the disease may lead to the risk of trial termination.? A comprehensive assessment by the researcher found that patients and their families could not accept the possible situation related to poor quality of life caused by scars after successful treatment.? Patients with poor systemic condition, multiple organ failure, serious systemic infection and severe wound infection, etc., the researchers comprehensively evaluated that the condition was unstable or the wound had no skin ability.?Other conditions deemed unsuitable for inclusion by the investigator.? Patients with simultaneous use of recombinant human epidermal growth factor gel as a wound treatment drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound surface measurement index;Wound healing effect; | — |
Secondary
| Measure | Time frame |
|---|---|
| Biochemical index detection; | — |
Countries
China
Contacts
Public ContactChuanan Shen
The Fourth Medical Center of Chinese PLA General Hospital
Outcome results
None listed