Diseases undergoing hysteroscopic surgery
Conditions
Interventions
Group K1:The patients were given 0.2 mg/kg ketamine combined with 2 mg/kg propofol intravenously and propofol 5 mg/kg/h by pump
Group K2:The patients were given 0.3 mg/kg ketamine combined with 2 mg/kg propofol intravenously and propofol 5 mg/kg/h by pump
Group K3:The patients were given 0.4 mg/kg ketamine combined with 2 mg/kg propofol intravenously and propofol 5 mg/kg/h by pump
Group K4:The patients were given 0.5 mg/kg ketamine combined with 2 mg/kg propofol intravenously and propofol 5 mg/kg/h by pump
Sponsors
Beijing Pinggu Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Hysteroscopic surgery (including curettage, induced abortion and curettage) ; aged 18-70 years; Asa Grade I-II; Sign the informed consent form
Exclusion criteria
Exclusion criteria: ?severe diseases of important organs such as heart, lung and brain;? allergic reaction to ketamine and propofol;?severe arrhythmia; ? suspected or long-term use of narcotic drugs and psychotropic drugs;?severe hypertension, high intracranial pressure or hyperthyroidism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of ambulatory salvage propofol; | — |
Secondary
| Measure | Time frame |
|---|---|
| MAP, HR, SpO2 at 5 min before anesthesia (t0), when eyelash reflex disappeared (T1), when uterus was enlarged (T2), when surgery was closed (T3) and when awake (T4).;Awakening time, operation time, total propofol dosage and propofol dosage of patients in four groups.;Perioperative adverse reactions of four groups of patients;Classification of uterine contraction pain degree and improved Aldrete score in the four groups at 5, 15 and 30 min after awakening.;Likert satisfaction score of patients and operators in four groups; | — |
Countries
China
Contacts
Public ContactZhang Zhijia
Beijing Pinggu Hospital
Outcome results
None listed