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Multimodal Analgesia Application by MDT team in Perioperative Period of Free Flap Reconstruction for Head and Neck Tumor Patients:A Randomized Clinical Trial

Multimodal Analgesia Application by MDT team in Perioperative Period of Free Flap Reconstruction for Head and Neck Tumor Patients:A Randomized Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079720
Enrollment
Unknown
Registered
2024-01-10
Start date
2022-08-08
Completion date
Unknown
Last updated
2024-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative pain

Interventions

Experimental group:Ultrasound-guided trigeminal nerve block anesthesia, 4ml of ropivacaine (0.3%)
Ultrasound-guided iliac fascia block anesthesia, 30ml of ropivacaine (0.3%)
Control group:Ultrasound-guided trigeminal nerve block anesthesia, 4ml of normal saline
Ultrasound-guided iliac fascia block anesthesia, 30ml of normal saline.

Sponsors

West China Hospital of Stomatology, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.Age from 18-85 years; 2.Accord with diagnostic criteria of oromaxillofacial tumor; 3.Without radiotherapy or chemotherapy before; 4.Accept vascularized anterolateral femoral free flap reparation simultaneously.

Exclusion criteria

Exclusion criteria: 1. Have malignant tumors in other parts of the body, or malignant tumors in head-and-neck have distant metastasis that cannot be treated by surgery; 2. Be allergic to multiple drugs or have recently been diagnosed with allergic diseases, especially sulfa allergy; 3.Unable to accurately locate the blocked anesthesia nerve during operation; 4. Participated in other clinical trials within 3 months; 5. With mental illness or unable to cooperate; 6. Severe heart, liver, kidney, blood system disease or systemic infection.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale (VAS) pain rating scale;

Secondary

MeasureTime frame
The start time of early out-of-bed activity;Blood pressure, heart rate, blood oxygen saturation; Appearance of digestive hemorrhage;IL-1, IL-6 and C-reactive protein of blood at postoperative 3 and 5 days;

Countries

China

Contacts

Public ContactJie Lin

West China Hospital of Stomatology, Sichuan University

1194164132@qq.com+86 135 5885 2310

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026