Perioperative pain
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age from 18-85 years; 2.Accord with diagnostic criteria of oromaxillofacial tumor; 3.Without radiotherapy or chemotherapy before; 4.Accept vascularized anterolateral femoral free flap reparation simultaneously.
Exclusion criteria
Exclusion criteria: 1. Have malignant tumors in other parts of the body, or malignant tumors in head-and-neck have distant metastasis that cannot be treated by surgery; 2. Be allergic to multiple drugs or have recently been diagnosed with allergic diseases, especially sulfa allergy; 3.Unable to accurately locate the blocked anesthesia nerve during operation; 4. Participated in other clinical trials within 3 months; 5. With mental illness or unable to cooperate; 6. Severe heart, liver, kidney, blood system disease or systemic infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale (VAS) pain rating scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| The start time of early out-of-bed activity;Blood pressure, heart rate, blood oxygen saturation; Appearance of digestive hemorrhage;IL-1, IL-6 and C-reactive protein of blood at postoperative 3 and 5 days; | — |
Countries
China
Contacts
West China Hospital of Stomatology, Sichuan University